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7 Thinking Mistakes Workaholics Make

Faulty thinking patterns contribute to why people stay stuck in workaholic habits when they'd like...

Anthropogenic combustion iron as a complex climate forcer

1.Luo, C. et al. Combustion iron distribution and deposition. Glob. Biogeochem. Cycles 22, GB1012 (2008).2.Mahowald, N. M. et al. Atmospheric iron deposition: Global distribution, variability, and hum...

Chromatin conformation regulates the coordination between DNA replication and transcription

Cell culture, cytometry and drug treatmentmES cells (kindly provided by A. Skoultchi, Albert Einstein College of Medicine, USA) were grown at 37 °C and 5% CO2 in Dulbecco’s modified Eagle’s med...

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Placental miR-340 mediates vulnerability to a...

Animal careICR/CD1 mice (Harlan Sprague

Chromatin conformation regulates the coordina...

Cell culture, cytometry and drug treatme

Cross-coupling polycondensation via C–O or ...

1.Günes, S., Neugebauer, H. & Saric

Publisher Correction: Nfat/calcineurin signal...

Open Access This article is licensed und

Vibrio vulnificus quorum-sensing molecule cyc...

ReagentsCyclo(L-Phe-L-Pro) (cFP) and Phe

Publisher Correction: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning

April 23, 2018/9:29 am

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as l...

Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity

April 23, 2018/9:29 am

ReagentsCyclo(L-Phe-L-Pro) (cFP) and Phe-Pro were purchased from Bachem (Bubendorf, Switzerland) and Sigma-Aldrich (St. Louis, MO, USA), respectively. Other cyclic dipeptides including biotinylated cF...

Reply to ‘Pitfalls in the quantitative imaging of glutathione in living cells’

April 23, 2018/9:29 am

Our group reported the first reversible reaction-based ratiometric probe—ThiolQuant Green—that can quantify glutathione (GSH) levels in living cells in 20151. Building on this work, we developed t...

Anthropogenic combustion iron as a complex climate forcer

April 23, 2018/9:29 am

1.Luo, C. et al. Combustion iron distribution and deposition. Glob. Biogeochem. Cycles 22, GB1012 (2008).2.Mahowald, N. M. et al. Atmospheric iron deposition: Global distribution, variability, and hum...

Relativistic magnetic reconnection driven by a laser interacting with a micro-scale plasma slab

April 23, 2018/9:14 am

Generation of relativistic jetsA sketch of the simulation setup is shown in Fig. 1a. A linearly polarized (in y direction) laser with normalized laser intensity a0 = eE0/mecω0 = 5 (intensity...

Quantifying absolute addressability in DNA origami with molecular resolution

April 23, 2018/9:14 am

Materials and buffersUnmodified, dye-labeled, and biotinylated DNA oligonucleotides were purchased from MWG Eurofins or Integrated DNA Technologies. DNA scaffold strands were purchased from Tilibit (p...

Heterogeneous Fe3 single-cluster catalyst for ammonia synthesis via an associative mechanism

April 23, 2018/9:14 am

N2 adsorption on supported Fe3 clusterThe FeMoco site of nitrogenase has been considered responsible for biological nitrogen fixation. Its performance in activating N2 molecule originates from the hig...

Identity prediction errors in the human midbrain update reward-identity expectations in the orbitofrontal cortex

April 23, 2018/9:14 am

SubjectsTwenty seven healthy human participants with no history of psychiatric illness (nine male, ages 19–34, mean ± SD = 25.5 ± 4.1 years) gave informed written consent to participat...

True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy

April 23, 2018/9:14 am

Protein expression and purificationFor many transcription factors, it is difficult to express full-length proteins at high levels in bacteria or eukaryotic cells25. Therefore, we cloned the DNA-bindin...

Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1

April 23, 2018/9:14 am

Upregulated BARD1/BRCA1 in TamR breast cancer cellsTamoxifen-resistant breast cancer cell lines were established from MCF7 and T47D as reported before21 (Fig. 1a and Supplementary Fig. 1a). In order...